Haupt M, Kurz A
Psychiatrische Klinik, Technischen Universität München.
Z Gesamte Inn Med. 1993 Dec;48(12):609-13.
Thirteen percent of all dementia disorders are potentially reversible. Hypothyroidism is among the most frequent causes of reversible dementias. Although it is generally accepted that dementia symptoms in hypothyroidism can be significantly reduced, many questions about the therapeutic efficacy are unexplained. It has not been systematically investigated which psychopathological symptoms respond well to thyroid hormone substitution, how long the treatment should last and whether duration of symptoms or severity of dementia have an influence on the degree of remission of psychopathological impairment. We investigated these questions in two prospectively studied cases with dementia in hypothyroidism.
所有痴呆症中有13%可能是可逆的。甲状腺功能减退是可逆性痴呆最常见的病因之一。尽管人们普遍认为甲状腺功能减退引起的痴呆症状可显著减轻，但关于治疗效果仍有许多问题无法解释。尚未系统研究哪些精神病理症状对甲状腺激素替代治疗反应良好、治疗应持续多长时间，以及症状持续时间或痴呆严重程度是否会对精神病理损害的缓解程度产生影响。我们对两例甲状腺功能减退伴痴呆的前瞻性研究病例进行了这些问题的调查。
