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韧带样纤维瘤病和高分化纤维肉瘤的细胞特征:一项电子显微镜研究

Cellular features in desmoid fibromatosis and well-differentiated fibrosarcomas: an electron microscopic study.

作者信息

Stiller D, Katenkamp D

出版信息

Virchows Arch A Pathol Anat Histol. 1975 Dec 31;369(2):155-64. doi: 10.1007/BF00433241.

DOI:10.1007/BF00433241
PMID:814705
Abstract

In the study presented here the ultrastructural cellular features of three desmoids and four well-differentiated fibrosarcomas were compared. Electron microscopically, the tumors were almost identical relative to qualitative traits. The majority of cells corresponded to fibroblast-like cells with certain morphological variations. Especially cells with characteristics of myofibroblasts must be emphasized, whereas cells with an organelle composition of classical fibroblasts were surprisingly seldom. Considering the relations of cells to each other and to vessels the prevailing origin of tumor cells from preexisting fibroblasts is suggested.

摘要

在本文所呈现的研究中,对三个硬纤维瘤和四个高分化纤维肉瘤的超微结构细胞特征进行了比较。在电子显微镜下,这些肿瘤在定性特征方面几乎相同。大多数细胞对应于具有某些形态学变异的成纤维细胞样细胞。尤其必须强调具有肌成纤维细胞特征的细胞,而具有典型成纤维细胞细胞器组成的细胞却出奇地少见。考虑到细胞彼此之间以及与血管的关系,提示肿瘤细胞主要起源于先前存在的成纤维细胞。

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Cellular features in desmoid fibromatosis and well-differentiated fibrosarcomas: an electron microscopic study.韧带样纤维瘤病和高分化纤维肉瘤的细胞特征:一项电子显微镜研究
Virchows Arch A Pathol Anat Histol. 1975 Dec 31;369(2):155-64. doi: 10.1007/BF00433241.
2
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引用本文的文献

1
[Desmoid-type fibromatosis (aggressive fibromatosis)].[韧带样型纤维瘤病(侵袭性纤维瘤病)]
Pathologe. 2005 Mar;26(2):117-26. doi: 10.1007/s00292-004-0742-1.
2
Heterogeneity of myofibroblast phenotypic features: an example of fibroblastic cell plasticity.肌成纤维细胞表型特征的异质性:成纤维细胞可塑性的一个例子。
Virchows Arch. 1994;425(1):3-24. doi: 10.1007/BF00193944.
3
Primary sarcoma of the gallbladder. A light and electronmicroscopical study.胆囊原发性肉瘤。光镜和电镜研究。

本文引用的文献

1
Malignant, fibroblastic tumors of the skin; clinical and pathological-anatomical studies of 129 cases of malignant, fibroblastic tumors from the cutaneous and subcutaneous layers observed at Radiumhemmet during the period 1927-1947.皮肤恶性纤维母细胞瘤;对1927年至1947年期间在镭疗医院观察到的129例来自皮肤和皮下层的恶性纤维母细胞瘤进行的临床及病理解剖学研究。
Acta Derm Venereol Suppl (Stockh). 1951;27:1-180.
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[THE MALIGNANCY OF TUMORS FROM THE CLINICAL, ANATOMOPATHOLOGIC, AND EXPERIMENTAL VIEWPOINTS].[从临床、解剖病理学及实验角度看肿瘤的恶性肿瘤]
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FIBROMA: A DANGEROUS DIAGNOSIS A REVIEW OF 205 CASES OF FIBROSARCOMA OF SOFT TISSUES.
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Fibroma of tendon sheath.腱鞘纤维瘤
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Inverted papillomas of nasal cavity and paranasal sinuses. Ultrastructural investigations on epithelial-stromal interface.
Virchows Arch A Pathol Anat Histol. 1982;397(2):215-26. doi: 10.1007/BF00442391.
6
Perifollicular, perisinusal and trabecular myofibroblasts in the human fetal spleen.人胎儿脾脏中的滤泡周、窦周和小梁肌成纤维细胞。
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Antibody specific to muscle actins in the diagnosis and classification of soft tissue tumors.肌肉肌动蛋白特异性抗体在软组织肿瘤诊断与分类中的应用
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Fibromatosis--a rare retroperitoneal tumour.
Langenbecks Arch Chir. 1990;375(1):51-4. doi: 10.1007/BF00186121.
9
Cytoskeletal characteristics of myofibroblasts in benign neoplastic and reactive fibroblastic lesions.良性肿瘤性和反应性纤维母细胞性病变中肌成纤维细胞的细胞骨架特征
Virchows Arch A Pathol Anat Histopathol. 1990;416(5):375-82. doi: 10.1007/BF01605141.
10
Morphological heterogeneity and phenotypical instability versus metastatic stability in the murine tumor model ER 15-P.小鼠肿瘤模型ER 15-P中形态学异质性和表型不稳定性与转移稳定性的对比
J Cancer Res Clin Oncol. 1992;118(5):349-60. doi: 10.1007/BF01294439.
纤维瘤:一种危险的诊断——205例软组织纤维肉瘤病例回顾
Br J Surg. 1964 Aug;51:607-12. doi: 10.1002/bjs.1800510814.
4
DESMOID TUMOURS. A SERIES OF 33 CASES.硬纤维瘤。33例病例系列
Acta Chir Scand. 1963 Oct;126:305-14.
5
Fibrosarcoma in infants and children.婴幼儿及儿童纤维肉瘤
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6
Fibrosarcoma arising in an extraabdominal desmoid tumor: report of case.
Proc Staff Meet Mayo Clin. 1962 Aug 15;37:443-51.
7
Dermal and fascial fibromatosis.皮肤和筋膜纤维瘤病
Ann Surg. 1954 Apr;139(4):453-67. doi: 10.1097/00000658-195404000-00009.
8
Intracytoplasmic collagen formations in desmoid fibromatosis.硬纤维瘤病中的胞浆内胶原形成
Am J Pathol. 1966 Sep;49(3):515-35.
9
Ultrastructure of mammalian venous capillaries, venules, and small collecting veins.哺乳动物静脉毛细血管、小静脉和小集合静脉的超微结构。
J Ultrastruct Res. 1968 Dec;25(5):452-500. doi: 10.1016/s0022-5320(68)80098-x.
10
Cytogenesis of schwannoma (neurilemoma), neurofibroma, dermatofibroma, and dermatofibrosarcoma as revealed by electron microscopy.电子显微镜揭示的施万细胞瘤(神经鞘瘤)、神经纤维瘤、皮肤纤维瘤和皮肤纤维肉瘤的细胞发生。
Am J Clin Pathol. 1968 Feb;49(2):141-54. doi: 10.1093/ajcp/49.2.141.