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聚丙烯酰胺凝胶电泳中的C3多态性

C3 polymorphism in polyacrylamide-gel electrophoresis.

作者信息

Schwamborn J, Freis H, Mauff G

出版信息

Vox Sang. 1976;30(3):223-30. doi: 10.1111/j.1423-0410.1976.tb02820.x.

Abstract

C3 polymorphism in polyacrylamide-gel electrophoresis was identified by crossed immunoelectrophoresis using anti-C3/C3c-serum. Through ageing, treatment of sera with cobra venom factor, endotoxin or with neuramindase, polymorphic bands were seen also in a conversion product and antigenically attributed to C3c. Rare phenotypes were observable in native C3 and in C3c.

摘要

采用抗C3/C3c血清,通过交叉免疫电泳法在聚丙烯酰胺凝胶电泳中鉴定出C3多态性。在血清老化、用眼镜蛇毒因子、内毒素或神经氨酸酶处理血清的过程中,在转化产物中也可见多态性条带,且抗原性归属于C3c。在天然C3和C3c中可观察到罕见的表型。

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