Vanamail P, Ramaiah K D, Das P K
Vector Control Research Centre, Pondicherry, India.
Acta Trop. 1993 Dec;55(4):237-47. doi: 10.1016/0001-706x(93)90081-l.
The risk of infection (RI) with Wuchereria bancrofti by vector mosquitoes has been conventionally estimated from the biting population of all age classes. This estimate of RI had no correlation with microfilaria (mf) prevalence and intensity of infection in humans. A new method for estimating RI from a resting population of Culex quinquefasciatus is proposed based on a longitudinal study in seventeen sites in Pondicherry, India. Unlike previous estimates, RI calculated by the present method considering the density of parous mosquitoes collected per man-hour and the mean number of infective stage larvae per parous mosquito significantly correlated with mf prevalence in humans during both early (r = 0.559; P = 0.038) and late in the control operation (r = 0.572; P = 0.033). RI varied significantly between the early and late in the control operation and different sites. On average, RI was reduced significantly during the control operation. Further epidemiological implications are discussed.
传统上，班氏吴策线虫通过媒介蚊虫的感染风险（RI）是根据所有年龄组的叮咬种群来估计的。这种RI估计值与人体微丝蚴（mf）流行率和感染强度无关。基于在印度本地治里17个地点进行的一项纵向研究，提出了一种根据致倦库蚊静止种群估计RI的新方法。与之前的估计不同，通过本方法计算的RI，考虑到每人工小时收集的已产卵蚊虫密度和每只已产卵蚊虫感染期幼虫的平均数量，在控制行动早期（r = 0.559；P = 0.038）和后期（r = 0.572；P = 0.033）均与人体mf流行率显著相关。在控制行动的早期和后期以及不同地点之间，RI差异显著。平均而言，在控制行动期间RI显著降低。文中还讨论了进一步的流行病学意义。
