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[对 Rh 阴性受试者进行 Rh 阳性血液计划免疫的结果]

[Results of planned immunization of Rh-negative subjects with Rh-positive blood].

作者信息

Kuśnierz G, Maślanka K

出版信息

Acta Haematol Pol. 1976;7(1):49-56.

PMID:814766
Abstract

Fifty-four men were immunized with Rh-positive blood for induction of anti-Rh antibodies. The method of immunization used allowed the planned effect to be obtained in 56% of cases. Starting with the 5th month after administration of the first antigenic stimulus the plasma of 17 subjects could be used for production of anti-D immunoglobulin. No reliable results were obtained in investigations of early phase of serologically undetectable immune response using the test of local haemolysis in gel (plaque-forming cells).

摘要

54名男性接受了Rh阳性血液免疫,以诱导产生抗Rh抗体。所采用的免疫方法在56%的病例中获得了预期效果。从首次给予抗原刺激后的第5个月开始,17名受试者的血浆可用于生产抗-D免疫球蛋白。使用凝胶局部溶血试验(斑块形成细胞)对血清学检测不到的免疫反应早期阶段进行研究,未获得可靠结果。

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