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白胸苦恶鸟(Amaurornis phoenicurus chinensis (Boddaert))肾脏中的羟基类固醇脱氢酶

Hydroxysteroid dehydrogenases in the kidney of white-breasted water hen, Amaurornis phoenicurus chinensis (Boddaert).

作者信息

Bhujle B V, Nadkarni V B

出版信息

Acta Histochem. 1975;54(2):284-9.

PMID:814773
Abstract

Histochemical localization of delta5-3beta-hydroxysteroid dehydrogenase (delta5-3beta-HSDH), 17beta-hydroxysteroid dehydrogenase (17beta-HSDH), 11beta-hydroxysteroid dehydrogenase (11beta-HSDH) and glucose-6-phosphate dehydrogenase (G-6-PDH) have been studied in the kidney of white-breasted water hen, Amaurornis phoenicurus chinensis. All these enzyme activities occurred in the proximal and distal convoluted and collecting tubules, however, the intensity of these enzyme activities was more in the proximal convoluted tubules. It is suggested that these enzymes might have a role in converting certain hydroxysteroids to ketosteroids during steroid excretion.

摘要

已对白胸苦恶鸟(Amaurornis phoenicurus chinensis)肾脏中的δ5-3β-羟基类固醇脱氢酶(δ5-3β-HSDH)、17β-羟基类固醇脱氢酶(17β-HSDH)、11β-羟基类固醇脱氢酶(11β-HSDH)和葡萄糖-6-磷酸脱氢酶(G-6-PDH)进行了组织化学定位研究。所有这些酶活性均出现在近端和远端曲管以及集合小管中,然而,这些酶活性的强度在近端曲管中更高。有人认为,这些酶在类固醇排泄过程中可能在将某些羟基类固醇转化为酮类固醇方面发挥作用。

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