Werneck A L, Checcacci-Balod T, Tuma G
Serviço de Neurologia, Hospital Central do Instituto de Assitência aos Servidores do Estado do Rio de Janeiro (HC/IASERJ), Brasil.
Arq Neuropsiquiatr. 1993 Dec;51(4):549-53. doi: 10.1590/s0004-282x1993000400023.
A thirty-six years old woman with myasthenia gravis developed cold intolerance after two years, and Hashimoto's thyroiditis diagnosis was established. Four years later she exhibited skin thickening (limited scleroderma). Laboratory and clinical findings suggested the CREST type of systemic sclerosis. Difficulty in scleroderma diagnosis is discussed, as overlap of syndromes. Hashimoto's thyroiditis and myasthenia gravis are infrequently associated. Occurrence of scleroderma and myasthenia gravis in the same patient is rare. The coincidence of these three disorders was not found in literature.
一名36岁的重症肌无力女性在两年后出现不耐寒症状,随后被诊断为桥本甲状腺炎。四年后,她出现皮肤增厚(局限性硬皮病)。实验室和临床检查结果提示为CREST型系统性硬化症。文中讨论了硬皮病诊断的困难之处,因为存在综合征重叠的情况。桥本甲状腺炎和重症肌无力很少同时出现。同一患者同时出现硬皮病和重症肌无力的情况罕见。文献中未发现这三种疾病同时存在的情况。