Bhalla R, Swedler W I, Lazarevic M B, Ajmani H S, Skosey J L
Department of Medicine, University of Illinois at Chicago 60612.
J Rheumatol. 1993 Aug;20(8):1409-10.
Myasthenia gravis is an autoimmune disease that is associated with antibodies to acetylcholine receptors. It is associated with other autoimmune diseases such as thyroiditis (10%), systemic lupus erythematosus (2-8%), rheumatoid arthritis (4-7%), Sjögren's syndrome and polymyositis. It is not commonly found with scleroderma. We describe a case of scleroderma developing in a patient 6 years after the onset of myasthenia gravis. HLA-B8/DR3 may play a role in the association of the 2 conditions.
重症肌无力是一种自身免疫性疾病，与抗乙酰胆碱受体抗体有关。它还与其他自身免疫性疾病相关，如甲状腺炎（10%）、系统性红斑狼疮（2 - 8%）、类风湿关节炎（4 - 7%）、干燥综合征和多发性肌炎。硬皮病中不常出现。我们描述了一例重症肌无力发病6年后患者发生硬皮病的病例。HLA - B8/DR3可能在这两种疾病的关联中起作用。
