Williams I T, Dwyer D M, Hirshorn E M, Bonito R C, Graham N M
Department of Epidemiology, Johns Hopkins University, School of Hygiene and Public Health, Baltimore, Md.
Arch Pediatr Adolesc Med. 1994 Apr;148(4):350-6. doi: 10.1001/archpedi.1994.02170040016003.
To describe the vaccination coverage of a population-based sample of Maryland children.
Historical cohort study using stratified cluster sampling. Strata were formed from five state regions and public and private schools within each region.
Random sample of elementary schools in Maryland.
Immunization records were obtained for a randomly selected cohort of 1938 first-grade children in Maryland.
Age of completion of recommended childhood vaccines and proportion of vaccines given simultaneously.
By first grade, 95.2% of the sample of Maryland children were documented to have received at least four doses of the diphtheria and tetanus toxoids and pertussis (DTP) vaccine, three doses of oral poliovirus (OPV) vaccine, and one dose of measles-mumps-rubella (MMR) vaccine. However, only 54.8% of children surveyed had achieved this level of immunization by 24 months of age. For children whose immunizations were up to date on their first birthday (78.7% of children surveyed), vaccine providers failed to administer one dose of DTP, OPV, and MMR vaccines to 30% of these children during the second year of life. Only 16.2% (n = 313) of children sampled received an MMR vaccination simultaneously with any dose of DTP or OPV vaccine.
This study shows that while immunization levels are very high at school entry, there are serious delays in vaccine administration before school entry. These delays are observed regardless of whether children are in public or private schools or attend school in an urban, suburban, or rural area. Physicians and health care providers could play an important role in age-appropriate vaccination by administering vaccines simultaneously.
描述以马里兰州儿童为基础的样本的疫苗接种覆盖率。
采用分层整群抽样的历史性队列研究。分层由该州五个地区以及每个地区内的公立和私立学校组成。
马里兰州小学的随机样本。
获取了马里兰州随机抽取的1938名一年级儿童队列的免疫记录。
完成推荐的儿童疫苗接种的年龄以及同时接种疫苗的比例。
到一年级时,记录显示马里兰州儿童样本中有95.2%至少接种了四剂白喉、破伤风类毒素和百日咳(DTP)疫苗、三剂口服脊髓灰质炎病毒(OPV)疫苗以及一剂麻疹-腮腺炎-风疹(MMR)疫苗。然而,在24个月龄时,只有54.8%的接受调查儿童达到了这一免疫水平。对于一岁生日时免疫接种情况最新的儿童(占接受调查儿童的78.7%),疫苗接种人员在这些儿童生命的第二年未能为其中30%的儿童接种一剂DTP、OPV和MMR疫苗。在抽取的儿童样本中,只有16.2%(n = 313)的儿童在接种任何一剂DTP或OPV疫苗的同时接种了MMR疫苗。
本研究表明,虽然入学时免疫接种水平很高,但入学前疫苗接种存在严重延迟。无论儿童就读于公立还是私立学校,或在城市、郊区还是农村上学,都会出现这些延迟情况。医生和医疗保健提供者通过同时接种疫苗,在适龄接种方面可以发挥重要作用。