Kremer I, Cohen E J, Eagle R C, Udell I, Laibson P R
Cornea Service, Wills Eye Hospital, Jefferson Medical College, Thomas Jefferson University, Philadelphia, PA 19107.
CLAO J. 1994 Jan;20(1):45-8.
Ten corneal specimens obtained at the time of penetrating keratoplasty for long-standing refractory Acanthamoeba keratitis were reviewed. Histopathologic findings included epithelial denudation and variable degrees of necrosis, inflammation, and cysts or trophozoites of acanthamoeba in the stroma. No blood vessels were found in the stroma despite the presence of long-standing corneal inflammation. The absence of corneal stromal neovascularization on biomicroscopic and histopathologic examination is a sign of Acanthamoeba keratitis.
回顾了10例因长期难治性棘阿米巴角膜炎行穿透性角膜移植术时获取的角膜标本。组织病理学发现包括上皮剥脱以及基质中不同程度的坏死、炎症，还有棘阿米巴囊肿或滋养体。尽管存在长期的角膜炎症，但基质中未发现血管。生物显微镜检查和组织病理学检查中角膜基质无新生血管是棘阿米巴角膜炎的一个征象。
