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犬猫败血性腹膜炎的术后并发症及预后指标:23例病例(1989 - 1992年)

Postoperative complications and prognostic indicators in dogs and cats with septic peritonitis: 23 cases (1989-1992).

作者信息

King L G

机构信息

Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia 19104-6010.

出版信息

J Am Vet Med Assoc. 1994 Feb 1;204(3):407-14.

PMID:8150698
Abstract

Medical records of 21 dogs and 2 cats treated for septic peritonitis were reviewed. Animals were between 1 and 12 years old, (mean, 6.5 years) and weighed between 6 and 51.4 kg (mean, 22.7 kg). Overall, 13 animals survived and were discharged from the hospital. Immediately after surgical correction of the underlying cause of peritonitis, most animals were tachycardic (mean heart rate, 148 beats/min; range, 80 to 204 beats/min), and many were hypotensive (mean arterial pressure, 84.4 mm of Hg; range, 44 to 156 mm of Hg). Hypotension was attributed to sepsis and hypovolemia secondary to extensive loss of fluid into the peritoneal cavity. Survivors did not differ from nonsurvivors with regard to mean arterial pressure immediately after surgery, and in most animals, hypotension could be corrected by IV administration of fluids. Three animals died after failing to respond to fluid treatment, despite concurrent administration of inotropic or pressor agents. Mean rate for crystalloid fluid administration was 12.8 ml/kg of body weight/h (range, 5 to 23.5 ml/kg/h) during the first 24 hours after surgery. Six of 23 animals had low urine output for a short time after surgery, but urine output increased when fluids were administered. Hypoalbuminemia developed in all animals (mean serum albumin concentration, 1.17 g/dl; range, 0.6 to 2.3 g/dl), and peripheral edema developed in 13. Neither lowest mean serum albumin concentration nor fluid administration rate was significantly different between animals that developed peripheral edema and those that did not. Fluid administration rates were significantly higher in nonsurvivors (15 ml/kg/h; range, 5.5 to 23.5 ml/kg/h) than in survivors (11 ml/kg/h; range, 5 to 17.5 ml/kg/h).(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

对21只犬和2只猫因感染性腹膜炎接受治疗的病历进行了回顾。动物年龄在1至12岁之间(平均6.5岁),体重在6至51.4千克之间(平均22.7千克)。总体而言,13只动物存活并出院。在对腹膜炎潜在病因进行手术纠正后,大多数动物出现心动过速(平均心率148次/分钟;范围80至204次/分钟),许多动物出现低血压(平均动脉压84.4毫米汞柱;范围44至156毫米汞柱)。低血压归因于败血症以及因大量液体渗入腹腔导致的血容量不足。存活者与未存活者术后即刻的平均动脉压无差异,并且在大多数动物中,低血压可通过静脉输注液体得到纠正。3只动物尽管同时使用了强心剂或升压药,但对液体治疗无反应后死亡。术后头24小时内晶体液输注平均速率为12.8毫升/千克体重/小时(范围5至23.5毫升/千克/小时)。23只动物中有6只术后短时间内尿量少,但输注液体后尿量增加。所有动物均出现低白蛋白血症(平均血清白蛋白浓度1.17克/分升;范围0.6至2.3克/分升),13只出现外周水肿。出现外周水肿的动物与未出现外周水肿的动物之间,最低平均血清白蛋白浓度和液体输注速率均无显著差异。未存活者的液体输注速率(15毫升/千克/小时;范围5.5至23.5毫升/千克/小时)显著高于存活者(11毫升/千克/小时;范围5至17.5毫升/千克/小时)。(摘要截短至250字)

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