Yoshida H, Sagawa M, Ohura H, Satoh N, Hasumi T, Okada S, Kondo T, Saito Y, Kobayashi S, Okaniwa G
Department of Surgery, Tohoku University, Sendai, Japan.
Kyobu Geka. 1994 Apr;47(4):333-5.
A case with thymic cancer who developed pulmonary cancer ten years after the initial surgery was reported. A 50-year-old man was admitted to our hospital due to SVC syndrome. Chest X-ray examinations including venogram showed a mass lesion at the superior mediastinum. The patient underwent surgical removal and reconstruction of SVC, followed by radio-chemotherapy. The histologic diagnosis was thymic squamous cell carcinoma. He was admitted to our hospital again ten years after the initial surgery under the diagnosis of pneumonia. Bronchoscopic examination revealed nodular lesions at the right upper lobe bronchus and lower lobe bronchus, those lesions were diagnosed with squamous cell carcinomas cytologically. Right pneumonectomy was performed and the diagnosis was confirmed pathologically. Postoperative course was uneventful as of 10 months after the operation. It was concluded that this case showed metachronous double cancer of the thymus and the lung, as well as synchronous multiple bronchogenic carcinomas, which, to our knowledge, has never been reported yet.
报告了一例胸腺癌患者，在初次手术后十年发生了肺癌。一名50岁男性因上腔静脉综合征入院。包括静脉造影在内的胸部X线检查显示上纵隔有一个肿块病变。患者接受了上腔静脉的手术切除和重建，随后进行了放化疗。组织学诊断为胸腺鳞状细胞癌。初次手术后十年，他因肺炎诊断再次入院。支气管镜检查显示右上叶支气管和下叶支气管有结节性病变，这些病变经细胞学诊断为鳞状细胞癌。进行了右肺切除术，病理诊断得到证实。截至术后10个月，术后病程平稳。结论是该病例显示了胸腺和肺的异时性双癌以及同时性多原发性支气管癌，据我们所知，此前从未有过相关报道。
