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癌症化疗的常见毒性

Common toxicities of cancer chemotherapy.

作者信息

Khoo K S, Ang P T, Lim A G

机构信息

Department of Medical Oncology, Singapore General Hospital.

出版信息

Singapore Med J. 1993 Oct;34(5):418-20.

PMID:8153689
Abstract

Sixty cancer patients who were receiving chemotherapy at an outpatient Oncology Centre were surveyed for their views on a list of treatment-related toxicities. The severity of each toxicity was assessed using a visual analogue scale. Sixty percent of patients felt that the overall toxicity was acceptable. Ten percent felt like giving up. Problem with venous access was named the worst toxicity by 37% of patients, followed by nausea and vomiting (19%), and long waiting time (11%). Male patients tended to tolerate chemotherapy better. The female patients were significantly more affected by hair loss than their male counterpart. Better understanding of the toxicities of chemotherapy as perceived by the patients themselves allows them to take appropriate measures in improving their quality of life.

摘要

在一家门诊肿瘤中心接受化疗的60名癌症患者就一系列与治疗相关的毒性反应发表了自己的看法。使用视觉模拟量表评估每种毒性反应的严重程度。60%的患者认为总体毒性是可以接受的。10%的患者想放弃。37%的患者将静脉通路问题列为最严重的毒性反应,其次是恶心和呕吐(19%)以及长时间等待(11%)。男性患者往往对化疗的耐受性更好。女性患者受脱发的影响明显比男性患者更大。更好地了解患者自身所感知的化疗毒性,有助于他们采取适当措施改善生活质量。

相似文献

1
Common toxicities of cancer chemotherapy.癌症化疗的常见毒性
Singapore Med J. 1993 Oct;34(5):418-20.
2
The pathophysiology of treatment-related nausea and vomiting in cancer patients: current models.癌症患者治疗相关恶心和呕吐的病理生理学:当前模型
Indian J Physiol Pharmacol. 2004 Jul;48(3):256-68.
3
Anticipatory nausea and vomiting in pediatric cancer patients.小儿癌症患者的预期性恶心和呕吐
Pediatrics. 1985 Mar;75(3):547-52.
4
Symptom experiences during chemotherapy treatment--with focus on nausea and vomiting.化疗治疗期间的症状体验——以恶心和呕吐为重点。
Eur J Oncol Nurs. 2006 Feb;10(1):21-9. doi: 10.1016/j.ejon.2005.03.007.
5
A pilot study of a relaxation technique for management of nausea and vomiting in patients receiving cancer chemotherapy.一项关于放松技巧对癌症化疗患者恶心呕吐管理作用的初步研究。
Cancer Nurs. 2007 Mar-Apr;30(2):163-7. doi: 10.1097/01.NCC.0000265007.87311.d0.
6
The efficacy and cost effectiveness of new antiemetic guidelines.新型止吐指南的疗效及成本效益
Oncol Nurs Forum. 1999 Oct;26(9):1453-8.
7
Intensity of chemotherapy-induced emesis and overall survival as determinants of a global utility score.化疗引起的呕吐强度和总生存期作为全球效用评分的决定因素。
Support Care Cancer. 2002 Nov;10(8):624-9. doi: 10.1007/s00520-002-0381-0. Epub 2002 Aug 2.
8
Changing patient perceptions of the side effects of cancer chemotherapy.改变患者对癌症化疗副作用的认知。
Cancer. 2002 Jul 1;95(1):155-63. doi: 10.1002/cncr.10630.
9
Conditioned aversions in pediatric cancer patients receiving chemotherapy.
J Dev Behav Pediatr. 1988 Apr;9(2):82-5.
10
Behavioral distress in pediatric patients with cancer receiving chemotherapy.接受化疗的癌症患儿的行为困扰
Pediatrics. 1989 Jul;84(1):103-10.

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