索马里丙型肝炎病毒性传播风险较低。

Low risk of sexual transmission of hepatitis C virus in Somalia.

作者信息

Watts D M, Corwin A L, Omar M A, Hyams K C

机构信息

Naval Medical Research Institute, Bethesda, Maryland 20852.

出版信息

Trans R Soc Trop Med Hyg. 1994 Jan-Feb;88(1):55-6. doi: 10.1016/0035-9203(94)90495-2.

DOI:10.1016/0035-9203(94)90495-2

PMID:8154002

Abstract

The prevalence in Somalia of antibody to hepatitis C virus (anti-HCV) was determined in a survey of 236 female prostitutes, 80 sexually transmitted disease (STD) clinic patients, 79 male soldiers, and 43 tuberculosis patients. Of 98 (22%) serum samples repeatedly anti-HCV reactive by first and second generation enzyme-linked immunosorbent assay kits, only 8 (1.8%) were anti-HCV positive by immunoblot assay (RIBA-2). Anti-HCV seropositivity by immunoblot assay was not associated with any risk group or with positive syphilis serology (found in 18% of subjects) or antibody to human immunodeficiency virus 1 (in 1.4% of subjects). These data indicate that sexual transmission of hepatitis C virus is not common in Somalia among sexually active populations, including female prostitutes and other groups at high risk of STDs and the acquired immune deficiency syndrome.

摘要

在一项针对236名女性性工作者、80名性传播疾病（STD）门诊患者、79名男性士兵和43名结核病患者的调查中，测定了索马里丙型肝炎病毒抗体（抗-HCV）的流行情况。在98份（22%）血清样本中，第一代和第二代酶联免疫吸附试验试剂盒检测结果反复显示抗-HCV呈反应性，而通过免疫印迹法（RIBA-2）检测，只有8份（1.8%）抗-HCV呈阳性。免疫印迹法检测的抗-HCV血清阳性与任何风险组均无关联，也与梅毒血清学阳性（18%的受试者中发现）或人类免疫缺陷病毒1抗体（1.4%的受试者中发现）无关。这些数据表明，在索马里，丙型肝炎病毒在包括女性性工作者以及其他性传播疾病和获得性免疫缺陷综合征高风险群体在内的性活跃人群中，通过性传播并不常见。