Erdmann E, Kirsch C M
Medizinische Klinik III, Universität zu Köln.
Z Kardiol. 1993;82 Suppl 5:143-7.
Myocardial stunning and myocardial hibernation gain increasing importance for the therapy of myocardial ischemia. It has been demonstrated that myocardial stunning may be reversible after successful reperfusion, although this may need weeks or even months. Similarly, noncontracting myocardial areas may regain contractile properties after successful dilatation of high grade stenoses or after bypass operation (myocardial hibernation). The diagnosis of myocardial stunning or myocardial hibernation usually is made by nuclear medicine (201Tl or 99Tc-MIBI). 201Tl-Imaging after 24 hours or after reinjection seems to be the best method to prove myocardial hibernation. Dobutamine stress echocardiography may gain importance in the future.
心肌顿抑和心肌冬眠在心肌缺血治疗中的重要性日益增加。已证实,成功再灌注后心肌顿抑可能是可逆的,尽管这可能需要数周甚至数月。同样,在高度狭窄成功扩张或搭桥手术后,无收缩功能的心肌区域可能恢复收缩特性(心肌冬眠)。心肌顿抑或心肌冬眠的诊断通常通过核医学(铊-201或锝-99m甲氧基异丁基异腈)进行。24小时后或再次注射后的铊-201显像似乎是证实心肌冬眠的最佳方法。多巴酚丁胺负荷超声心动图未来可能会变得更加重要。