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[儿童急性淋巴细胞白血病和淋巴肉瘤的脑脊液研究]

[Cerebrospinal fluid studies in acute lymphoblastic leukemia and lymphosarcomas in children].

作者信息

Bondarenko L V

出版信息

Zh Nevrol Psikhiatr Im S S Korsakova. 1993;93(5):56-7.

PMID:8154221
Abstract

The author presents data of cerebrospinal fluid (CSF) examinations in children with acute lymphoblastic leukemia and lymphosarcomas. CSF syndromes are described which permit a conclusion on increased permeability of the hematoencephalic barrier in this patient population. CSF changes polymorphism, cyclic pattern are demonstrated, as is a functional specificity of the hematoencephalic barrier in acute lymphoblastic leukemia and lymphosarcomas consisting in a trend to CSF normalization. The author claims that CSF remissions may occur which do not coincide with findings of clinical and morphologic examinations of the CNS in children with hemoblastoses.

摘要

作者展示了急性淋巴细胞白血病和淋巴肉瘤患儿脑脊液(CSF)检查的数据。描述了脑脊液综合征,据此可推断该患者群体中血脑屏障通透性增加。脑脊液变化的多态性、周期性模式得到了证实,急性淋巴细胞白血病和淋巴肉瘤中血脑屏障的功能特异性表现为脑脊液有趋于正常化的趋势。作者声称,血液系统恶性肿瘤患儿脑脊液缓解情况可能与中枢神经系统的临床和形态学检查结果不一致。

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