Lamba P A, Pandey P K, Sarin G S, Mathur M D
Guru Nanak Eye Centre, Department of Microbiology and Ophthalmology, Maulana Azad Medical College, New Delhi, India.
Acta Ophthalmol (Copenh). 1993 Dec;71(6):833-5. doi: 10.1111/j.1755-3768.1993.tb08609.x.
Serum sialic acid levels were measured in 16 patients with sympathetic ophthalmitis, 36 with neglected traumatic uveitis following penetrating injury and 40 healthy subjects. There was no significant alteration of its level in patients with traumatic uveitis. However, its level was significantly elevated in patients with sympathetic ophthalmitis. It was high even in the early stage of the disease. It decreased significantly at the remission stage. It is proposed that measurement of sialic acid level in serum can be used as a diagnostic aid when the diagnosis of sympathetic ophthalmitis remains doubtful on clinical grounds. The extent of rise in its level may be considered a good parameter of the degree of severity of sympathetic ophthalmitis. It may also act as a useful tool to evaluate the drug efficacy in this disease.
对16例交感性眼炎患者、36例穿透伤后被忽视的外伤性葡萄膜炎患者和40名健康受试者进行了血清唾液酸水平测定。外伤性葡萄膜炎患者的血清唾液酸水平无明显变化。然而，交感性眼炎患者的血清唾液酸水平显著升高。甚至在疾病早期也是如此。在缓解期显著下降。建议当交感性眼炎的临床诊断仍有疑问时，血清唾液酸水平的测定可作为一种诊断辅助手段。其水平升高的程度可被视为交感性眼炎严重程度的一个良好参数。它也可作为评估该病药物疗效的有用工具。
