Schaefer A E, Fishman M, Adler L T
J Immunol. 1976 Apr;116(4):1157-62.
The induction of specific immunologic tolerance and its transfer has been studied in the in vitro response of unprimed rabbit spleen cells to solubilized phage antigens. Evidence presented shows that only viable cells transfer tolerance and that the responsible cells appear devoid of membrane-bound antigen but are sensitive to anti-thymocyte serum. It appears, therefore, that although the in vitro response to solubilized S-T2 has no demonstrable requirement for T "helper" cells, it is subject to the action of T "supp "suppressor" cells.
在未致敏兔脾细胞对可溶性噬菌体抗原的体外反应中，对特异性免疫耐受的诱导及其转移进行了研究。所提供的证据表明，只有活细胞能转移耐受，且起作用的细胞似乎没有膜结合抗原，但对抗胸腺细胞血清敏感。因此，尽管对可溶性S-T2的体外反应对T“辅助”细胞没有明显需求，但它受T“抑制”细胞的作用影响。
