Laínez R M, Losada M, Nieto E, Olona M
Escuela Universitaria de Enfermería Valle Hebron, Barcelona.
Enferm Infecc Microbiol Clin. 1994 Jan;12(1):4-8.
We performed a follow-up study of 104 consecutive patients who underwent cardiac surgery to ascertain the following: 1) the incidence of nosocomial pneumonia (NP) in this patient population; 2) the differences in the incidence of NP between patients who underwent coronary artery bypass grafting (CABG) vs. valvular replacement (VR), and 3) the identification of risk factors which predispose patients to the development of NP.
The study included 104 patients of which 49 underwent VR, 43 CABG and 12 who had both procedures performed simultaneously. Six of the 104 patients developed NP (5.7%). Five of these patients had undergone VR where as opposed to only one in the CABG group. Pulmonary hypertension preoperatively was a risk factor for the development of NP. Of the 49 patients in the VR group, 46 had pulmonary artery pressures (PAP) recorded, and from their 23 (50%) had pulmonary hypertension. However, 4 of the 5 (80%) patients who developed NP had elevated PAP. The mortality among patients with NP was high. Sixty six percent of patients (4/6) with NP died in comparison to the 10 deaths (10.2%) among 92 patients without NP (p = 0.002).
A trend in the development of NP was observed in patients who underwent valve replacement as opposed to CABG. Because of the small number of patients who developed pneumonia in the study population statistical significance cannot be reached. Pulmonary hypertension in the post operative period is a risk factor for the development of NP. Mortality among patients who develop NP is significantly high (p = 0.002).
我们对104例连续接受心脏手术的患者进行了一项随访研究,以确定以下内容:1)该患者群体中医院获得性肺炎(NP)的发生率;2)接受冠状动脉旁路移植术(CABG)与瓣膜置换术(VR)的患者之间NP发生率的差异;3)识别使患者易患NP的危险因素。
该研究纳入104例患者,其中49例行VR,43例行CABG,12例同时进行了这两种手术。104例患者中有6例发生NP(5.7%)。这些患者中有5例接受了VR,而CABG组只有1例。术前肺动脉高压是发生NP的一个危险因素。VR组的49例患者中,46例记录了肺动脉压(PAP),其中23例(50%)有肺动脉高压。然而,发生NP的5例患者中有4例(80%)PAP升高。NP患者的死亡率很高。NP患者中有66%(4/6)死亡,而92例无NP患者中有10例死亡(10.2%)(p = 0.002)。
与CABG相比,接受瓣膜置换术的患者中观察到NP发生的一种趋势。由于研究人群中发生肺炎的患者数量较少,无法达到统计学意义。术后肺动脉高压是发生NP的一个危险因素。发生NP的患者死亡率显著较高(p = 0.002)。