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[链黑菌素对L系细胞增殖的影响]

[Effect of streptovaricin on the multiplication of L line cells].

作者信息

Kavetskiĭ R E, Shulklinov V A, Bundiuk L S, Lysiuk L P

出版信息

Vopr Onkol. 1978;24(9):41-6.

PMID:81565
Abstract

An inhibitor of the reverse trascriptase-streptovaricin in a dose of 4 mkg/ml would induce an increase of the DNA amount in L cell nuclei, while its dosage of 8 mkg/ml decrease the amount of DNA, resulting in the differentiation of some population cells. Streptovaricin inhibited the L cell multiplication, rendering no significant effect on that of normal fibroblasts of C3H mice culture.

摘要

剂量为4微克/毫升的逆转录酶-链黑菌素抑制剂会导致L细胞核中DNA量增加,而其8微克/毫升的剂量会减少DNA量,从而导致一些群体细胞分化。链黑菌素抑制L细胞增殖,对C3H小鼠培养的正常成纤维细胞增殖没有显著影响。

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