Paetau R, Hämäläinen M, Hari R, Kajola M, Karhu J, Larsen T A, Lindahl E, Salonen O
Low Temperature Laboratory, Helsinki University of Technology, Espoo, Finland.
Epilepsia. 1994 Mar-Apr;35(2):275-84. doi: 10.1111/j.1528-1157.1994.tb02431.x.
Magnetoencephalographic (MEG) discharges were recorded with multichannel superconducting quantum interference device (SQUID) gradiometers in 13 young candidates for epilepsy surgery. The sources of epileptic activity were related to generators of somatosensory and auditory evoked cortical responses and projected on magnetic resonance imaging (MRI) scans. Seven subjects had restricted or regional MEG foci, located in the frontoopercular (1), sensorimotor (3), perisylvian (1), mesiotemporal (1), or temporooccipital cortex (1). The MEG foci in the 3 patients who underwent operation agreed with the intracranial findings. Findings in the other patients emphasize the need to collect further data to define the ultimate role of MEG in preoperative evaluation of epilepsy.
使用多通道超导量子干涉装置(SQUID)梯度仪记录了13名年轻癫痫手术候选者的脑磁图(MEG)放电情况。癫痫活动的来源与体感和听觉诱发皮层反应的发生器相关,并投射在磁共振成像(MRI)扫描上。7名受试者有局限或区域性MEG病灶,分别位于额眶部(1例)、感觉运动区(3例)、外侧裂周围(1例)、颞叶内侧(1例)或颞枕叶皮质(1例)。3例接受手术的患者的MEG病灶与颅内检查结果相符。其他患者的检查结果强调,需要收集更多数据来确定MEG在癫痫术前评估中的最终作用。