Berger T M, Berger M F, Hoffman A D, Zimmerman D, Tönz O
Department of Paediatrics, Children's Hospital of Lucrene, Switzerland.
Eur J Pediatr. 1994 Feb;153(2):100-2. doi: 10.1007/BF01959217.
A 4-week-old male infant was admitted to the hospital with acute gastrointestinal bleeding and marked coagulopathy secondary to vitamin K malabsorption in the presence of cholestasis. Physical examination revealed hepatomegaly and cutaneous haemangiomas. Ultrasonography, CT, and MRI demonstrated a multifocal vascular process and allowed the diagnosis of infantile hepatic haemangioendothelioma to be made without the use of more invasive diagnostic procedures. To avoid high-output congestive heart failure, the patient was treated with oral corticosteroids. After 5 months, rapid involution of the vascular malformations ensued. At age 2 years, a magnetic resonance scan confirmed complete resolution of the hepatic haemangioendothelioma.
一名4周大的男婴因急性胃肠道出血和胆汁淤积导致维生素K吸收不良继发明显凝血障碍而入院。体格检查发现肝肿大和皮肤血管瘤。超声、CT和MRI显示为多灶性血管病变,无需采用更具侵入性的诊断程序即可诊断为婴儿肝血管内皮瘤。为避免高输出量充血性心力衰竭,该患者接受了口服皮质类固醇治疗。5个月后,血管畸形迅速消退。在2岁时,磁共振扫描证实肝血管内皮瘤已完全消退。