Roy A, Mukherjee S, Bhattacharya S, Adhya S, Chakraborty P
S.D. Hospital, Kurseong.
Indian J Pathol Microbiol. 1993 Oct;36(4):361-9.
Combined histological and bacteriological investigations of 800 specimens of nonpregnant endometrial curettings of 15 to 60 years age group of hill women of Darjeeling District were carried out for detection of tuberculous endometritis. The principal complaints were infertility (47.5 per cent), abnormal uterine bleeding (30.75 per cent), amenorrhoea (11.25 per cent), leucorrhoea (6.25 per cent), and miscellaneous conditions (pelvic pain and pyometra) (4.25 per cent) cases. By histological examination alone, only 10.9 per cent cases could be diagnosed while by combined study the incidence rate was 11.8 percent, an increase in the diagnostic acumen by more than 10.3 per cent. Bacteriological study was of greater value in doubtful cases where there was absence of tuberculous granuloma or epithelioid cell but presence of nonspecific inflammatory cells along with variable degree of necrosis of glandular epithelia. The incidence of M.tuberculosis was 97.7 percent while that of atypical mycobacteria was 2.3 per cent. Thus simultaneous use of culture and biopsy yielded better results. Our prevalence is a little higher than other reports from India. In cold weather at a high altitude, the tubercle bacilli survive longer in fomites which serve as important sources of infection in Darjeeling. Women of third decade are more frequently affected (43.2 per cent).
对大吉岭地区15至60岁山区非妊娠妇女的800份子宫内膜刮除标本进行了组织学和细菌学联合研究，以检测结核性子宫内膜炎。主要症状包括不孕（47.5%）、子宫异常出血（30.75%）、闭经（11.25%）、白带异常（6.25%）以及其他情况（盆腔疼痛和积脓）（4.25%）。仅通过组织学检查，仅能诊断出10.9%的病例，而通过联合研究，发病率为11.8%，诊断敏锐度提高了超过10.3%。在可疑病例中，细菌学研究更有价值，这些病例中没有结核性肉芽肿或上皮样细胞，但存在非特异性炎性细胞以及不同程度的腺上皮坏死。结核分枝杆菌的发生率为97.7%，非典型分枝杆菌的发生率为2.3%。因此，同时使用培养和活检可产生更好的结果。我们的患病率略高于印度的其他报告。在高海拔地区的寒冷天气中，结核杆菌在污染物中存活时间更长，这是大吉岭地区重要的感染源。三十多岁的女性受影响更为频繁（43.2%）。
