Kusama M, Kusama K, Hayashi S, Sunouchi T, Chu L, Moro I
Faculty of Home Economics, Tokyo Kasei University, Japan.
J Nihon Univ Sch Dent. 1993 Dec;35(4):241-3. doi: 10.2334/josnusd1959.35.241.
The levels of natural antibody against Thomsen-Friedenreich (TF) antigen in sera of patients with various cancers and infectious diseases were examined by an enzyme-linked immunosorbent assay (ELISA) and compared with those of healthy donors. The levels of antibody against TF antigen in sera of patients with adenocarcinomas such as gastric, pancreatic and colorectal cancers were lower than those of patients with hepatoma, pyelonephritis and pneumonia. These findings may reflect the expression of TF-antigen in adenocarcinoma tissues.
通过酶联免疫吸附测定（ELISA）检测了各种癌症和传染病患者血清中针对汤姆森-弗里德赖希（TF）抗原的天然抗体水平，并与健康供体的水平进行了比较。胃癌、胰腺癌和结直肠癌等腺癌患者血清中针对TF抗原的抗体水平低于肝癌、肾盂肾炎和肺炎患者。这些发现可能反映了TF抗原在腺癌组织中的表达。
