Kaczmarek J C, Kates R, Rau F, Kohorn E, Curry S
Department of Obstetrics and Gynecology, Hartford Hospital, Connecticut.
Obstet Gynecol. 1994 May;83(5 Pt 2):842-4.
Intrapartum rupture of the uterus in a primiparous patient is an exceedingly rare event. This case report describes uterine rupture in a woman with previous invasive hydatidiform mole.
A 27-year-old primiparous woman with a history of gestational trophoblastic neoplasia treated successfully with chemotherapy experienced intrapartum uterine rupture with subsequent neonatal death. Magnetic resonance imaging of the uterus had shown evidence of myometrial invasion by the mole. Weakening of the uterine wall secondary to myometrial destruction is believed to have caused the uterine rupture.
Many women will attempt to conceive following treatment for gestational trophoblastic neoplasia. It is important to determine whether there is any local invasion of the myometrium, as this can affect intrapartum management in subsequent pregnancies.
初产妇分娩期子宫破裂是极其罕见的事件。本病例报告描述了一名既往有侵袭性葡萄胎的女性发生子宫破裂的情况。
一名27岁初产妇，有妊娠滋养细胞肿瘤病史，经化疗成功治疗，分娩期发生子宫破裂，随后新生儿死亡。子宫磁共振成像显示有葡萄胎侵袭子宫肌层的证据。子宫肌层破坏继发子宫壁变薄被认为是导致子宫破裂的原因。
许多女性在妊娠滋养细胞肿瘤治疗后会尝试受孕。确定子宫肌层是否有局部侵袭很重要，因为这会影响后续妊娠的分娩期管理。
