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PH domains and phospholipases--a meaningful relationship?

作者信息

Parker P J, Hemmings B A, Gierschik P

机构信息

Imperial Cancer Research Fund, London, UK.

出版信息

Trends Biochem Sci. 1994 Feb;19(2):54-5. doi: 10.1016/0968-0004(94)90031-0.

DOI:10.1016/0968-0004(94)90031-0
PMID:8160264
Abstract
摘要

相似文献

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PH domains and phospholipases--a meaningful relationship?PH结构域与磷脂酶——一种有意义的关系？
Trends Biochem Sci. 1994 Feb;19(2):54-5. doi: 10.1016/0968-0004(94)90031-0.
2
Effects of mutations in pleckstrin homology domain on beta-adrenergic receptor kinase activity in intact cells.普列克底物蛋白同源结构域突变对完整细胞中β-肾上腺素能受体激酶活性的影响。
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3
G proteins and beta ARK: a new twist for the coiled coil.G蛋白与β-肾上腺素能受体激酶：卷曲螺旋的新变化
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4
The beta-adrenergic receptor kinase interacts with the amino terminus of the G protein beta subunit.
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5
Binding of PH domains of beta-adrenergic receptor kinase and beta-spectrin to WD40/beta-transducin repeat containing regions of the beta-subunit of trimeric G-proteins.
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6
The adrenergic receptors.
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7
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Membrane binding of phospholipases C-beta 1 and C-beta 2 is independent of phosphatidylinositol 4,5-bisphosphate and the alpha and beta gamma subunits of G proteins.磷脂酶C-β1和C-β2的膜结合不依赖于磷脂酰肌醇4,5-二磷酸以及G蛋白的α和βγ亚基。
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Regulation by cAMP-dependent protein kinease of a G-protein-mediated phospholipase C.环磷酸腺苷依赖性蛋白激酶对G蛋白介导的磷脂酶C的调节作用
Nature. 1996 Jul 4;382(6586):83-7. doi: 10.1038/382083a0.

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Structural analyses of the Slm1-PH domain demonstrate ligand binding in the non-canonical site.Slm1-PH 结构域的结构分析表明配体在非经典位点结合。
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The ordered visual transduction complex of the squid photoreceptor membrane.鱿鱼光感受器膜中有序的视觉转导复合体。
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Activation of phospholipase C gamma by PI 3-kinase-induced PH domain-mediated membrane targeting.磷脂酰肌醇3激酶诱导的PH结构域介导的膜靶向作用激活磷脂酶Cγ 。
EMBO J. 1998 Jan 15;17(2):414-22. doi: 10.1093/emboj/17.2.414.
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G-protein betagamma subunits antagonize protein kinase C-dependent phosphorylation and inhibition of phospholipase C-beta1.G蛋白βγ亚基拮抗蛋白激酶C依赖性磷酸化并抑制磷脂酶C-β1。
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Expression, characterization, and crystallization of the catalytic core of rat phosphatidylinositide-specific phospholipase C delta 1.大鼠磷脂酰肌醇特异性磷脂酶Cδ1催化核心的表达、表征及结晶
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The yeast and mammalian isoforms of phosphatidylinositol transfer protein can all restore phospholipase C-mediated inositol lipid signaling in cytosol-depleted RBL-2H3 and HL-60 cells.磷脂酰肌醇转移蛋白的酵母和哺乳动物同工型均可在胞质溶胶缺失的RBL-2H3和HL-60细胞中恢复磷脂酶C介导的肌醇脂质信号传导。
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Molecular cloning, expression and regulatory activity of G alpha 11- and beta gamma-subunit-stimulated phospholipase C-beta from avian erythrocytes.来自禽类红细胞的Gα11和βγ亚基刺激的磷脂酶C-β的分子克隆、表达及调节活性
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A new inositol 1,4,5-trisphosphate binding protein similar to phospholipase C-delta 1.一种类似于磷脂酶C-δ1的新型肌醇1,4,5-三磷酸结合蛋白。
Biochem J. 1996 Jan 1;313 ( Pt 1)(Pt 1):319-25. doi: 10.1042/bj3130319.
10
CRAC, a cytosolic protein containing a pleckstrin homology domain, is required for receptor and G protein-mediated activation of adenylyl cyclase in Dictyostelium.CRAC是一种含有普列克底物蛋白同源结构域的胞质蛋白，在盘基网柄菌中，它是受体和G蛋白介导的腺苷酸环化酶激活所必需的。
J Cell Biol. 1994 Sep;126(6):1537-45. doi: 10.1083/jcb.126.6.1537.