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法洛四联症根治术后肺功能不全对心室功能的影响:放射性核素心室造影评估及临床发现

The influence of pulmonary insufficiency on ventricular function following total correction of Fallot's tetralogy: evaluation using radionuclide ventriculography and clinical findings.

作者信息

Arsan S, Yorgancioğlu C, Paşaoğlu I, Erbaş B, Bozer A Y

机构信息

Department of Thoracic and Cardiovascular Surgery, Hacettepe University Faculty of Medicine, Ankara.

出版信息

Turk J Pediatr. 1993 Oct-Dec;35(4):323-31.

PMID:8160286
Abstract

Long-standing pulmonary insufficiency after repair of tetralogy of Fallot may adversely affect ventricular function. We evaluated 20 patients postoperatively by radionuclide ventriculography and clinical findings after total correction of tetralogy of Fallot. Patients were divided into two groups as follows: Group I patients (10) had no pulmonary insufficiency; Group II patients (10) had moderate or severe pulmonary insufficiency. Preoperatively, there was no difference between groups in terms of age, functional capacity according to the New York Heart Association criteria, hemoglobin and hematocrit level, cardiothoracic ratio, McGoon ratio, left and right ventricular ejection fraction, cardiac output or cardiac index. Postoperatively, right ventricular ejection fraction was 40.10 +/- 2.28 in Group I and 29.5 +/- 2.86 in Group II, p < 0.01. Left ventricular ejection fraction was 59.3 +/- 2.90 in Group I and 50.9 +/- 4.19 in Group II, p < 0.01. Radionuclide ventriculography is a useful means of identifying right ventricular dysfunction following repair of tetralogy of Fallot. The dysfunction appears significantly worse in patients with pulmonary insufficiency.

摘要

法洛四联症修复术后长期存在的肺功能不全可能会对心室功能产生不利影响。我们通过放射性核素心室造影和临床检查结果对20例法洛四联症完全矫正术后的患者进行了评估。患者被分为以下两组:第一组患者(10例)无肺功能不全;第二组患者(10例)有中度或重度肺功能不全。术前,两组患者在年龄、根据纽约心脏协会标准的功能能力、血红蛋白和血细胞比容水平、心胸比率、麦戈恩比率、左心室和右心室射血分数、心输出量或心脏指数方面均无差异。术后,第一组右心室射血分数为40.10±2.28,第二组为29.5±2.86,p<0.01。第一组左心室射血分数为59.3±2.90,第二组为50.9±4.19,p<0.01。放射性核素心室造影是识别法洛四联症修复术后右心室功能障碍的一种有用方法。肺功能不全患者的功能障碍明显更严重。

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引用本文的文献

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Heart. 2000 Oct;84(4):416-20. doi: 10.1136/heart.84.4.416.