Gulieva S A, Samedov S I
Vopr Med Khim. 1994 Mar-Apr;40(2):54-6.
40 rabbits were used in the experiments, where 10 animals were in control group, and 3 groups of the animals were treated with naphthalene oil obtained from various pit-holes NN 39, 54 and 88. The treatment course included 10 applications of naphthalene oil, which was placed on lateral body surface, 10 x 10 cm, a dose of 1.0 ml/kg, within 10 min. A state of lipid peroxidation was evaluated by measurement of hydroperoxides, diene conjugates and malonic dialdehyde in rabbit blood. Some decrease in content of lipoperoxides was observed in rabbits after the course of naphthalene oil treatment and the oil from the pit-hole 54 exhibited the highest effect. These results may be involved in evaluation of the naphthalene oil medicinal effects as well as in working out recommendations to use the naphthalene oil not from usual reservoir, but namely from pit-hole 54 for treatment of patients with impaired lipid metabolism.
40只兔子用于实验，其中10只动物作为对照组，另外3组动物用从不同坑洞NN 39、54和88获取的萘油进行处理。治疗过程包括10次涂抹萘油，将其涂于身体侧面10×10厘米的区域，剂量为1.0毫升/千克，在10分钟内完成。通过测量兔血中的氢过氧化物、二烯共轭物和丙二醛来评估脂质过氧化状态。在萘油治疗过程后，观察到兔子体内脂过氧化物含量有所降低，且来自坑洞54的油效果最为显著。这些结果可能有助于评估萘油的药用效果，以及制定相关建议，即使用并非来自常规储存源、而是来自坑洞54的萘油来治疗脂质代谢受损的患者。
