Deriabin P G, Gavrilov V I, Loginova N V, Karpova E F
Vopr Virusol. 1975 Mar-Apr(2):235-8.
Japanese encephalitis virus contained in the medium of chronically infected VERO-K43 cell cultures was shown to be sensitive to the effect of RNA-ase, resistant to treatment with urea, to have no hemagglutinating activity. After 2 passages in suckling mouse brain the virus lost its sensitivity to RNA-ase, was inactivated by urea, and its hemagglutinating activity was restored. The importance of Japanese encephalitis virus variability in the mechanism of chronic infection of cell cultures is discussed.
在慢性感染的VERO - K43细胞培养物培养基中所含的日本脑炎病毒被证明对RNA酶的作用敏感，对尿素处理有抗性，且无血凝活性。在乳鼠脑内传代2次后，该病毒失去了对RNA酶的敏感性，被尿素灭活，并且其血凝活性得以恢复。文中讨论了日本脑炎病毒变异性在细胞培养物慢性感染机制中的重要性。
