[Syringoma and trisomy 21].

Two cases of syringoma associated with trisomy 21 are reported. The first case concerned a 29-year old trisomic woman with multiple syringomas of the eyelids, and the second case concerned a 44-year old trisomic woman with disseminated but not eruptive syringomas. The syringoma-trisomy 21 associated is not fortuitous, being 31 times more frequent than in the general population. The "usual" location of syringomas on the eyelids has given rise to many reports, but disseminated syringomas have been reported in only four cases.