Wolff B G, Dozois R R
Mayo-Clinic, Rochester, MN 33905.
Ann Chir. 1993;47(10):963-6.
The ileal pouch-anal anastomosis procedure has become the procedure of choice for many patients with chronic ulcerative colitis and with familial adenomatous polyposis. The results in several thousand patients from many institutions are excellent. In an attempt to reduce the number of bowel movements and to improve continence, a modification of the original hand-sewn anastomosis has been proposed in which and ileal pouch distal rectal anastomosis is performed which, in turn, leaves from 1 to 3 cm of diseased rectal mucosa above the anal canal. Advocates of this modification state that resting pressure is higher and that continence, particularly nighttime continence, is significantly improved. Despite some apparent advantage, with less of a decrease in resting pressure and an advantage in ease of operation, no advantage over hand-sewn ileal pouch-anal anastomosis has been shown to-date in two prospective randomized trials in functional results or in complication rate. In addition, it is uncertain what the significance is of the small strip of diseased mucosa that i retained as far a recurrent disease, continuation of extra-intestinal manifestations of inflammatory bowel disease, and with risk of carcinoma. We believe that the stapled ileal pouch distal rectal anastomosis should be avoided in patients who have severe chronic ulcerative colitis low in the rectum or if there is proximal chronic ulcerative colitis with dysplasia or carcinoma. We also feel that this procedure should be avoided in patients with familial adenomatous polyposis and in patients who have extra-intestinal manifestations of inflammatory bowel disease.(ABSTRACT TRUNCATED AT 250 WORDS)
回肠储袋肛管吻合术已成为许多慢性溃疡性结肠炎和家族性腺瘤性息肉病患者的首选手术方式。来自许多机构的数千例患者的手术效果极佳。为了减少排便次数并改善控便能力,有人提出了对原始手工缝合吻合术的一种改良方法,即进行回肠储袋与直肠远端吻合,这样在肛管上方会保留1至3厘米的病变直肠黏膜。这种改良方法的支持者称,静息压力更高,控便能力,尤其是夜间控便能力有显著改善。尽管有一些明显优势,如静息压力下降较少且操作更简便,但在两项前瞻性随机试验中,到目前为止,在功能结果或并发症发生率方面,与手工缝合的回肠储袋肛管吻合术相比并无优势。此外,保留的一小条病变黏膜对于复发性疾病、炎症性肠病肠外表现的持续以及癌变风险的意义尚不确定。我们认为,对于直肠下段有严重慢性溃疡性结肠炎的患者,或存在近端慢性溃疡性结肠炎伴发育异常或癌变的患者,应避免使用吻合器进行回肠储袋与直肠远端吻合术。我们还认为,对于家族性腺瘤性息肉病患者以及有炎症性肠病肠外表现的患者,也应避免使用该手术方式。(摘要截选至250词)