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[X射线造影剂的信号特征及其在磁共振成像中与钆-DTPA的相互作用]

[Signal characteristics of x-ray contrast media and their interaction with gadolinium-DTPA in MRT].

作者信息

Kopka L, Funke M, Fischer U, Vosshenrich R, Schröder M, Grabbe E

机构信息

Abteilung Röntgendiagnostik I, Georg-August-Universität Göttingen.

出版信息

Rofo. 1994 Apr;160(4):349-52. doi: 10.1055/s-2008-1032436.

Abstract

T1 and T2 weighted signals derived from various radiological contrast media were studied during MRT spin-echo sequences. In addition, the interaction between radiological contrast media and Gadolinium-DTPA concerning T1 signals was evaluated. Ionic (ioxitalaminic acid) and non-ionic radiological contrast media (Iopromid, Iotrolan) were used in diagnostic concentrations. Measurements were carried out with a superconductive magnet of 1.5 Tesla. Radiological contrast media produced significantly higher signals than a physiological sodium chloride solution in T1-weighted spin-echo sequences. Even small amounts (15% of total volume) of radiological contrast media during T1-weighted spin-echo sequences led to a significant reduction (about 25%) of the signal intensity of a 2 mM Gadolinium-DTPA solution. This may lead to diagnostic problems, as was shown in a series of 25 MR arthrograms of the shoulder. It is recommended than an interval of at least 6 hours should elapse between the use of a radiological contrast medium and an MRT examination.

摘要

在磁共振成像(MRT)自旋回波序列期间,研究了源自各种放射造影剂的T1加权和T2加权信号。此外,还评估了放射造影剂与钆-二乙三胺五乙酸(Gadolinium-DTPA)在T1信号方面的相互作用。使用了诊断浓度的离子型(碘克沙酸)和非离子型放射造影剂(碘普罗胺、碘曲仑)。测量是在一台1.5特斯拉的超导磁体上进行的。在T1加权自旋回波序列中,放射造影剂产生的信号明显高于生理氯化钠溶液。即使在T1加权自旋回波序列期间少量(总体积的15%)的放射造影剂也会导致2 mM钆-二乙三胺五乙酸溶液的信号强度显著降低(约25%)。这可能会导致诊断问题,如在一系列25例肩部磁共振关节造影中所示。建议在使用放射造影剂和进行MRT检查之间至少间隔6小时。

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