Kopka L, Funke M, Fischer U, Vosshenrich R, Schröder M, Grabbe E
Abteilung Röntgendiagnostik I, Georg-August-Universität Göttingen.
Rofo. 1994 Apr;160(4):349-52. doi: 10.1055/s-2008-1032436.
T1 and T2 weighted signals derived from various radiological contrast media were studied during MRT spin-echo sequences. In addition, the interaction between radiological contrast media and Gadolinium-DTPA concerning T1 signals was evaluated. Ionic (ioxitalaminic acid) and non-ionic radiological contrast media (Iopromid, Iotrolan) were used in diagnostic concentrations. Measurements were carried out with a superconductive magnet of 1.5 Tesla. Radiological contrast media produced significantly higher signals than a physiological sodium chloride solution in T1-weighted spin-echo sequences. Even small amounts (15% of total volume) of radiological contrast media during T1-weighted spin-echo sequences led to a significant reduction (about 25%) of the signal intensity of a 2 mM Gadolinium-DTPA solution. This may lead to diagnostic problems, as was shown in a series of 25 MR arthrograms of the shoulder. It is recommended than an interval of at least 6 hours should elapse between the use of a radiological contrast medium and an MRT examination.
在磁共振成像（MRT）自旋回波序列期间，研究了源自各种放射造影剂的T1加权和T2加权信号。此外，还评估了放射造影剂与钆-二乙三胺五乙酸（Gadolinium-DTPA）在T1信号方面的相互作用。使用了诊断浓度的离子型（碘克沙酸）和非离子型放射造影剂（碘普罗胺、碘曲仑）。测量是在一台1.5特斯拉的超导磁体上进行的。在T1加权自旋回波序列中，放射造影剂产生的信号明显高于生理氯化钠溶液。即使在T1加权自旋回波序列期间少量（总体积的15%）的放射造影剂也会导致2 mM钆-二乙三胺五乙酸溶液的信号强度显著降低（约25%）。这可能会导致诊断问题，如在一系列25例肩部磁共振关节造影中所示。建议在使用放射造影剂和进行MRT检查之间至少间隔6小时。
