Lequesne M, Lamotte J, Samson M
Service de Rhumatologie, Hôpital Léopold Bellan, Paris.
Rev Rhum Ed Fr. 1993 May;60(5 Pt 2):23S-29S.
The main Indices of Quality of Life used in rheumatology and their aims and applications are surveyed. Their use in osteoarthritis implies a few issues that are addressed in a critical manner. Indices of Quality of Life are useful to measure deficiency resulting from osteoarthritis by comparison with other rheumatic diseases, as rheumatoid arthritis, connective tissue diseases, fibromyalgia... They are sensitive enough for apraising the domains improved by a radical treatment such as joint replacement. However, their scores are only slightly changing in most of the drug trials, in which the more simple functional indices seem demonstrative enough. Last but no least, they are notably time consuming for both the patient and the physician.
本文综述了风湿病学中使用的主要生活质量指标及其目的和应用。它们在骨关节炎中的应用存在一些问题,本文将对此进行批判性探讨。与类风湿关节炎、结缔组织病、纤维肌痛等其他风湿性疾病相比,生活质量指标有助于衡量骨关节炎导致的功能缺陷。它们足够敏感,能够评估诸如关节置换等根治性治疗所改善的领域。然而,在大多数药物试验中,它们的评分变化不大,而更简单的功能指标似乎已足够说明问题。最后但同样重要的是,它们对患者和医生来说都非常耗时。