Hannerz J, Greitz D, Ericson K
Department of Neurology, Karolinska Hospital, Stockholm, Sweden.
Headache. 1994 Feb;34(2):95-8. doi: 10.1111/j.1526-4610.1994.hed3402095.x.
Sixteen patients with chronic periorbital venous vasculitis without nerve involvement and 9 patients with active episodic cluster headache were studied as to cerebrospinal fluid (CSF) pressure. Eighty-one percent of the patients with chronic and 33% with episodic symptoms had pathologically increased CSF pressure. Magnetic resonance imaging of the brains in the chronic group showed empty sella in 60%, cerebral atrophy in 21% and white matter lesions with high signal intensity on T2 weighted sequences in 29%. Abnormal obesity was found in 31% of the patients with chronic periorbital venous vasculitis under 60 years of age. Venous vasculitis is suggested as a cause of intracranial hypertension, empty sella, and endocrinologic dysfunctions.
对16例无神经受累的慢性眶周静脉血管炎患者和9例发作性丛集性头痛活跃期患者的脑脊液压力进行了研究。慢性患者中有81%、发作性症状患者中有33%的脑脊液压力病理性升高。慢性组患者脑部的磁共振成像显示,60%为空蝶鞍,21%为脑萎缩,29%在T2加权序列上有高信号强度的白质病变。60岁以下的慢性眶周静脉血管炎患者中有31%存在异常肥胖。提示静脉血管炎是颅内高压、空蝶鞍和内分泌功能障碍的一个病因。