Meyer C, de Manzini N, Rohr S, Thiry C L, Perim-Kalil F C, Bachellier-Billot C
Service de Chirurgie Générale et Digestive, C.H.U. de Strasbourg-Hautepierre.
J Chir (Paris). 1993 Dec;130(12):501-6.
The authors report 1,000 cases of cholecystectomy for cholelithiasis, excluding all cases with associated common bile duct surgery. The aim of the study was to compare two groups of cholecystectomies, one of 500 laparotomic procedures, evaluated retrospectively, and one of 500 laparoscopic ones, evaluated prospectively. Sex ratio was the same in both groups, and mean age was higher in the second group (54 vs 60) (p < 0.05): acute cholecystitis ratio was similar in both groups (23% vs 19%; NS). During the laparoscopic period, 84 laparotomic interventions were performed (17%), with a 0% mortality and a 18% morbidity rate. Mean operating time was 69' in the first group vs 91' in the second one, with a mean hospital stay of 11 vs 4.5 days (p < 0.001). Mortality rate was 1% vs 0% (p < 0.03) for laparotomic and laparoscopic procedures, and morbidity rate was respectively 11% and 1% (p < 0.001). Conversion rate in laparoscopic surgery was 7%. Two cases (0.4%) in laparoscopic group had a common bile duct lesion diagnosed intraoperatively and 1 case (0.2%) had a residual stone in common bile duct. Laparoscopic surgery is at present the standard technique for the treatment of cholelithiasis and laparotomic cholecystectomy seems only indicated when laparoscopic procedure is contraindicated or impossible.
作者报告了1000例因胆结石而行胆囊切除术的病例,排除了所有合并胆总管手术的病例。该研究的目的是比较两组胆囊切除术,一组是500例经腹手术,进行回顾性评估,另一组是500例腹腔镜手术,进行前瞻性评估。两组的性别比例相同,第二组的平均年龄较高(54岁对60岁)(p<0.05):两组的急性胆囊炎比例相似(23%对19%;无显著性差异)。在腹腔镜手术期间,进行了84例经腹干预(17%),死亡率为0%,发病率为18%。第一组的平均手术时间为69分钟,第二组为91分钟,平均住院时间分别为11天和4.5天(p<0.001)。经腹手术和腹腔镜手术的死亡率分别为1%和0%(p<0.03),发病率分别为11%和1%(p<0.001)。腹腔镜手术的转化率为7%。腹腔镜组有2例(0.4%)术中诊断为胆总管病变,1例(0.2%)胆总管残留结石。目前,腹腔镜手术是治疗胆结石的标准技术,开腹胆囊切除术似乎仅在腹腔镜手术禁忌或无法进行时才适用。