Mommersteeg T J, Blankevoort L, Kooloos J G, Hendriks J C, Kauer J M, Huiskes R
Biomechanics Section, University of Nijmegen, The Netherlands.
J Orthop Res. 1994 Mar;12(2):238-45. doi: 10.1002/jor.1100120213.
It is generally recognized that the mechanical properties of soft connective tissues are affected by their structural components. We documented collagen density distributions in human knee ligaments to quantify differences in density within and between these ligaments. In order to explain the variations in mechanical properties within and between different knee ligaments as described in the literature, the distributions of collagen density were correlated with these biomechanical findings. Human knee ligaments were shown to be nonhomogeneous structures with regard to collagen density. The anterior bundles of all ligaments contained significantly more collagen mass per unit of volume than the posterior bundles did. The percentage differences between the anterior and posterior bundles, in relation to the posterior bundles, were about 25% for the anterior cruciate ligament (ACL) and the collateral ligaments and about 10% for the posterior cruciate ligament (PCL). Along the cruciate ligaments, the central segments had higher collagen densities than did segments adjacent to the ligament insertions (ACL 9%, PCL 24%). The collagen density in the ACL was significantly lower than that in the other ligaments. These variations within and between the ligaments correlate well with the variations in mechanical properties described in the literature; however, other structural differences have to be taken into account to fully explain the variations in mechanical properties from the structural components.
人们普遍认为，软结缔组织的力学性能受其结构成分的影响。我们记录了人类膝关节韧带中的胶原蛋白密度分布，以量化这些韧带内部以及相互之间密度的差异。为了解释文献中描述的不同膝关节韧带内部以及相互之间力学性能的变化，将胶原蛋白密度分布与这些生物力学研究结果进行了关联。结果表明，就胶原蛋白密度而言，人类膝关节韧带是不均匀的结构。所有韧带的前束每单位体积所含的胶原蛋白质量均明显多于后束。前束与后束之间的百分比差异，以前后束的百分比表示，前交叉韧带（ACL）和侧副韧带约为25%，后交叉韧带（PCL）约为10%。沿交叉韧带，中央段的胶原蛋白密度高于韧带附着点附近的段（ACL为9%，PCL为24%）。ACL中的胶原蛋白密度明显低于其他韧带。韧带内部以及相互之间的这些变化与文献中描述的力学性能变化密切相关；然而，为了从结构成分充分解释力学性能的变化，还必须考虑其他结构差异。
