Sposto M R, Mendes-Giannini M J, Moraes R A, Branco F C, Scully C
Department of Oral Diagnosis, Faculty of Odontology, UNESP, Araraquara, Brazil.
J Oral Pathol Med. 1994 Feb;23(2):85-7. doi: 10.1111/j.1600-0714.1994.tb00262.x.
Paracoccidioidomycosis (South American blastomycosis) is a systemic mycosis which can be associated with oral lesions. This study on a group of 14 patients showed oral lesions mainly on the gingival or alveolar mucosa, with pulmonary involvement detectable on chest radiography in most. Microscopic detection of the fungus on a direct smear showed positive results in all 14 patients. Serological investigations including immunodiffusion, counterimmunoelectrophoresis and immunoblot were also positive in 100% of cases. The results suggest that direct smear together with serology may obviate the need for lesional biopsy for the diagnosis of oral paracoccidioidomycosis.
副球孢子菌病（南美芽生菌病）是一种可伴有口腔损害的系统性真菌病。这项针对14例患者的研究显示，口腔损害主要出现在牙龈或牙槽黏膜，大多数患者胸部X线检查可发现肺部受累。14例患者的真菌直接涂片镜检均呈阳性结果。包括免疫扩散、对流免疫电泳和免疫印迹在内的血清学检查结果也均为100%阳性。结果表明，直接涂片检查联合血清学检查可能无需进行损害活检即可诊断口腔副球孢子菌病。
