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所谓的“未成熟牙瘤”:病例报告及与成釉细胞纤维牙本质瘤的组织学比较

So-called "immature dentinoma": a case presentation and histological comparison with ameloblastic fibrodentinoma.

作者信息

Takeda Y

机构信息

Department of Oral Pathology, School of Dentistry, Iwate Medical University, Morioka, Japan.

出版信息

J Oral Pathol Med. 1994 Feb;23(2):92-6. doi: 10.1111/j.1600-0714.1994.tb00264.x.

Abstract

The existence of the "dentinoma" as an independent entity has not been fully accepted, recently being regarded as an ameloblastic fibroma with formation of dentin and named an ameloblastic fibrodentinoma. However, there are histological differences between the several cases reported previously as "immature dentinoma" and the ameloblastic fibrodentinoma. This paper presents a case report of a dentin-forming intraosseous benign tumor without any histological features of ameloblastic fibroma. The patient was a 30-year-old woman with a rather well-circumscribed intraosseous lesion of the mandibular left premolar area. Histologically, the lesion consisted of dentin-like tissue with a tubular structure and globular calcifications, numerous epithelial strands and islands without enamel organ-like structure, and a cellular fibrous component without a primitive dental papilla-like appearance. The present case and a review of the literature suggest that epithelial elements in odontogenic fibroma-like lesions may occasionally have an inductive effect for dentin or dentin-like tissue formation.

摘要

“牙本质瘤”作为一个独立实体的存在尚未得到充分认可,近来被视为伴有牙本质形成的成釉细胞纤维瘤,并被命名为成釉细胞纤维牙本质瘤。然而,先前报道为“未成熟牙本质瘤”的几例病例与成釉细胞纤维牙本质瘤之间存在组织学差异。本文报告一例骨内形成牙本质的良性肿瘤,其无成釉细胞纤维瘤的任何组织学特征。患者为一名30岁女性,下颌左前磨牙区有一个边界相当清晰的骨内病变。组织学上,该病变由具有管状结构和球状钙化的牙本质样组织、众多无釉器样结构的上皮条索和岛以及无原始牙乳头样外观的细胞性纤维成分组成。本病例及文献复习提示,牙源性纤维瘤样病变中的上皮成分偶尔可能对牙本质或牙本质样组织的形成具有诱导作用。

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