Yasuda K, Shibata K
Research Division, Teikoku Hormone Mfg. Co., Ltd.
Nihon Rinsho. 1994 Mar;52(3):672-8.
NMR is so convenient way to get stereochemical information of an organic compound that organic chemists have readily taken advantage of its spectra to investigate its stereochemistry by means of chemical shifts, coupling constants, nuclear Overhauser effect, etc. Especially in the steroid field, there have been reported many studies for determination of chemical structure and analysis of conformation. It is exemplified how NMR is in steroid chemistry.
核磁共振是获取有机化合物立体化学信息的便捷方法,有机化学家已欣然利用其光谱,通过化学位移、耦合常数、核Overhauser效应等手段来研究其立体化学。特别是在甾体领域,已有许多关于化学结构测定和构象分析的研究报道。这例证了核磁共振在甾体化学中的应用。