Rarick T L, Tchabo J G
Georgetown University Medical Center, Washington, DC.
Obstet Gynecol. 1994 May;83(5 Pt 1):761-5.
To study the relation between the timing of the postpartum examination and the postpartum Papanicolaou smear.
One hundred eighty-four women in labor at Arlington Community Hospital were randomized to receive their postpartum Papanicolaou smear at 4, 6, or 8 weeks after delivery. Samples from the exocervix and endocervix were obtained and submitted to the pathology department, which was unaware of the study.
Twenty-three women were lost to follow-up. Among 161 women who had a postpartum examination, 48 (30%) had it at 4 weeks, 61 (38%) at 6 weeks, and 52 (32%) at 8 weeks. The groups were similar with respect to age, ethnicity, gravidity, parity, marital status, number of sexual partners, age at first intercourse, history of cervical infections, previous history of abnormal Papanicolaou smears, and cervical surgery. Among the 139 women who had a normal prenatal smear, 26 (59%) had an abnormal smear at 4 weeks (24 [92%] had inflammation, one [4%] had inflammation with nuclear atypia, and one [4%] had cervical intraepithelial neoplasia [CIN] III), 17 (32%) were abnormal at 6 weeks (15 [88%] had inflammation, one [6%] had inflammation with nuclear atypia, and one [6%] had CIN III), and 12 (28%) were abnormal at 8 weeks (11 [92%] had inflammation and one [8%] had inflammation with nuclear atypia). There were no differences in the distribution of abnormal Papanicolaou smears at the repeat smear done 3 months after the postpartum examination.
The incidence of abnormal Papanicolaou smears increased as the postpartum interval decreased from 8 to 4 weeks.
研究产后检查时间与产后巴氏涂片之间的关系。
将阿灵顿社区医院的184名分娩妇女随机分为三组，分别在产后4周、6周或8周接受产后巴氏涂片检查。从子宫颈外口和子宫颈内口获取样本并提交给病理科，病理科人员对该研究不知情。
23名妇女失访。在161名接受产后检查的妇女中，48名（30%）在4周时进行检查，61名（38%）在6周时进行检查，52名（32%）在8周时进行检查。这些组在年龄、种族、孕次、产次、婚姻状况、性伴侣数量、初次性交年龄、宫颈感染史、既往巴氏涂片异常史和宫颈手术史方面相似。在139名产前涂片正常的妇女中，26名（59%）在4周时涂片异常（24名[92%]有炎症，1名[4%]有炎症伴核异型，1名[4%]有宫颈上皮内瘤变[CIN]III级），17名（32%）在6周时异常（15名[88%]有炎症，1名[6%]有炎症伴核异型，1名[6%]有CIN III级），12名（28%）在8周时异常（11名[92%]有炎症，1名[8%]有炎症伴核异型）。产后检查3个月后复查涂片时，异常巴氏涂片的分布没有差异。
随着产后间隔从8周缩短至4周，异常巴氏涂片的发生率增加。
