Poulain J, Luffau G, Pery P
C R Acad Hebd Seances Acad Sci D. 1975 Dec 15;281(23):1933-4.
Nippostrongylus brasiliensis infected rats responded with the formation of hemagglutinating antibodies in both serum and intestinal secretions. After the first infection seric antibody titers were quite weak but increased sharply after challenge. Intestinal secretion hemagglutinines remained at constant level after both infections. This result represents a new approach in our understanding of the immune mechanism towards this parasite in rats.
巴西日圆线虫感染的大鼠血清和肠道分泌物中均会产生血凝抗体。初次感染后血清抗体滴度很弱,但再次感染后会急剧上升。两次感染后肠道分泌物中的血凝素水平保持恒定。这一结果为我们理解大鼠针对这种寄生虫的免疫机制提供了新的思路。