[Effects of LSD-25 on the cell cycle of Pleurodeles Waltlii Michah. embryos treated at the end of gastrulation].

LSD-25 lengthens the G2 and M phases of the cell cycle in embryos treated at the late gastrula stage and labelled with tritiated thymidine. This antimitotic effect of LSD-25 is comparable to the similar effect of colchicine or vinblastine, but is weaker. Cell distribution among the phases of the cell cycle has been studied by cytophotometry; mitotic index has been calculated, and curves of labelled mitoses variation have been established.