Sherman S J, Boyer L V, Sibley W A
Department of Neurology, University of Arizona, Tucson 85724.
Stroke. 1994 May;25(5):1065-7. doi: 10.1161/01.str.25.5.1065.
We report the clinical and neuroimaging findings of a patient who sustained multiple cerebral infarcts after the ingestion of concentrated hydrogen peroxide solution sold as a "health food" product.
An 84-year-old man sustained focal neurological deficits immediately after ingesting 30 mL of 35% hydrogen peroxide solution. Physical examination disclosed a left hemiparesis, frontal release signs, and cerebellar dysfunctions. Magnetic resonance imaging revealed multiple cerebral and cerebellar infarctions in the anterior, middle, and posterior vascular territories.
The likely mechanism of pathogenesis involves cerebral oxygen gas embolization. The use of hyperbaric therapy should be considered in treating hydrogen peroxide poisoning.
我们报告了一名患者的临床和神经影像学检查结果,该患者在摄入作为“健康食品”出售的浓缩过氧化氢溶液后发生了多发性脑梗死。
一名84岁男性在摄入30毫升35%过氧化氢溶液后立即出现局灶性神经功能缺损。体格检查发现左侧偏瘫、额叶释放征和小脑功能障碍。磁共振成像显示大脑前、中、后血管区域有多发性脑梗死和小脑梗死。
发病机制可能涉及脑氧气栓塞。在治疗过氧化氢中毒时应考虑使用高压氧治疗。