Wong W C, Tsang K K
Division of Gastroenterology, Department of Internal Medicine, Veterans General Hospital, Taipei, Taiwan, Republic of China.
Vaccine. 1994;12(3):229-34. doi: 10.1016/0264-410x(94)90199-6.
Chronic hepatitis B infection is hyperendemic in Taiwan. A massive hepatitis B vaccination programme has been implemented since 1984. Eight years after its introduction, the HBsAg carrier rate in young children has decreased fivefold, and the protective efficacy of the vaccines is estimated to be 85%. Despite the successful execution of the programme, a certain percentage of the population declined vaccination. The reasons for not completing or for delaying the vaccination schedule are discussed. In conclusion, a flexible and target-specific campaign should be undertaken in the future.
慢性乙型肝炎感染在台湾地区高度流行。自1984年起实施了大规模乙肝疫苗接种计划。该计划实施八年后，幼儿中的乙肝表面抗原（HBsAg）携带者率下降了五倍，疫苗的保护效力估计为85%。尽管该计划执行成功，但仍有一定比例的人群拒绝接种疫苗。文中讨论了未完成或延迟接种计划的原因。总之，未来应开展灵活且针对特定目标人群的宣传活动。
