Wölfle K D, Mayer H, Tietze W, Bruijnen H, Mayer B, Loeprecht H
Klinik für Gefäss- und Thoraxchirurgie, Zentralklinikum Augsburg.
Zentralbl Chir. 1994;119(2):115-23.
In a prospective study, the results following PTA of 30 short stenoses > 70% in 17 infrainguinal arterial bypass grafts were examined. The stenoses were detected after a mean follow-up of 7.2 months by Duplex-ultrasound. The initial success rate after PTA was 100%. After an average time of 4.6 months recurrent graft stenoses were identified in 8 bypasses and 1 patient experienced graft thrombosis. Overall 8 of the 17 patients with stenotic grafts were treated by PTA alone during a mean follow-up of 11.7 months. Using life-table analysis, primary and assisted primary patency rates were each 100% at 1 month and 41 and 86% at 2 years. The efficacy of thrombolysis in 36 occluded grafts (graft age > 30 days) with clinical symptoms of incomplete ischaemia was analyzed retrospectively. After successful lysis in 61% (22/36), 15 grafts underwent additional procedures including PTA (10), vein patch angioplasty (4) and distal graft extension (1). Following successful initial graft salvage, primary cumulative patency and limb salvage rates were 45 and 72% at 1 month and 16 and 51% at 3 years. PTA of primary graft stenoses may be regarded as an acceptable initial therapeutic option, but has some limitations in providing sustained patency. Grafts initially salvaged with lysis do not have favourable short and long-term patency.
在一项前瞻性研究中,对17例下肢动脉旁路移植术中30处狭窄程度>70%的短段狭窄进行经皮腔内血管成形术(PTA)后的结果进行了检查。这些狭窄在平均随访7.2个月后通过双功超声检测到。PTA后的初始成功率为100%。平均4.6个月后,8条旁路移植血管出现复发性狭窄,1例患者发生移植血管血栓形成。在平均11.7个月的随访期间,17例移植血管狭窄患者中有8例仅接受了PTA治疗。采用寿命表分析,1个月时的初级通畅率和辅助初级通畅率均为100%,2年时分别为41%和86%。对36例有不完全缺血临床症状的闭塞移植血管(移植血管龄>30天)进行溶栓疗效的回顾性分析。61%(22/36)成功溶栓后,15条移植血管接受了包括PTA(10条)、静脉补片血管成形术(4条)和移植血管远端延长术(1条)在内的额外手术。在成功进行初始移植血管挽救后,1个月时的初级累积通畅率和肢体挽救率分别为45%和72%,3年时分别为16%和51%。原发性移植血管狭窄的PTA可被视为一种可接受的初始治疗选择,但在提供持续通畅方面有一些局限性。最初通过溶栓挽救的移植血管在短期和长期内的通畅情况不佳。