Roca González A, Palomeque Rico A, Pastor Durán X, Molinero Egea C, Jiménez González R
Servicio de Pediatría, Hospital Clinic, Barcelona.
An Esp Pediatr. 1993 Dec;39(6):513-6.
A group of 13 children, aged 2 to 14 years, and diagnosed with Guillain-Barré syndrome has been analyzed. Clinical features and outcome were retrospectively studied. In 75% of the patients there was an infectious illness previous to the neurologic symptoms and in four children the etiologic agent was demonstrated. Motor deficits affecting the limbs and muscle stretch reflexes were absent in all thirteen patients. Cranial nerve involvement showed-up in 46%. Meningitic symptoms occurred in 62% of the cases. One of the children developed the Fisher syndrome variant. Two patients required assisted ventilation. Three children showed associated immunologic abnormalities, with one of the patients having a selective IgA deficiency, another child showing an increment in IgE and the other Kawasaki syndrome. We have not demonstrated differences in the outcome between the patients with corticoid treatment.
对一组13名年龄在2至14岁、被诊断为吉兰-巴雷综合征的儿童进行了分析。对临床特征和预后进行了回顾性研究。75%的患者在出现神经症状之前有感染性疾病，4名儿童的病原体得到了证实。13名患者均无影响肢体的运动功能障碍和肌肉牵张反射。46%的患者出现颅神经受累。62%的病例出现脑膜炎症状。其中一名儿童出现了费舍尔综合征变异型。两名患者需要辅助通气。三名儿童表现出相关的免疫异常，一名患者患有选择性IgA缺乏症，另一名儿童IgE升高，还有一名患有川崎综合征。我们没有证明接受皮质类固醇治疗的患者在预后方面存在差异。
