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[儿童肠道病毒感染:530例患者的临床和流行病学研究结果(1984 - 1991年)]

[Enteroviral infections in children: clinical and epidemiological findings in 530 patients (1984-1991)].

作者信息

Moral Gil L, Rubio Calduch E M, Broto Escapa P, Caballero Requero E, Calico Bosch I, Bertrán Sangues J M

机构信息

Servicio de Bacteriología, Ciudad Sanitaria y Universitaria Valle de Hebrón, Barcelona.

出版信息

An Esp Pediatr. 1993 Dec;39(6):521-7.

PMID:8166408
Abstract

Between 1984 and 1991 enteroviral infections have been detected in a total of 530 patients. This type of infection was more frequent during the first years of life, among males and at the end of spring. The most common complaints (70% of the cases) included gastrointestinal manifestation, respiratory symptoms or febrile illness (viremia caused by enterovirus in two patients). Enterovirus was isolated in 25 patients with intussusception. Concurrent acute heart disease was diagnosed in six patients and Guillain-Barré syndrome in four. Enterovirus was isolated from the cerebrospinal fluid in 79 patients (15%), the majority of whom were infants under 2 months of age or children from 3 to 7 years old. Differences between these two age groups are discussed. Moreover, there were 16 patients with aseptic meningitis probably caused by enterovirus. In the spring of 1987, an epidemic outbreak of enteroviral meningitis was detected, particularly among infants. This outbreak coincided with others reported in different geographic areas of our country.

摘要

1984年至1991年间,共检测出530例肠道病毒感染患者。这类感染在生命的最初几年、男性以及春末更为常见。最常见的症状(70%的病例)包括胃肠道表现、呼吸道症状或发热性疾病(两名患者由肠道病毒引起病毒血症)。从25例肠套叠患者中分离出肠道病毒。6例患者被诊断为并发急性心脏病,4例为格林-巴利综合征。79例患者(15%)的脑脊液中分离出肠道病毒,其中大多数是2个月以下的婴儿或3至7岁的儿童。讨论了这两个年龄组之间的差异。此外,有16例无菌性脑膜炎患者可能由肠道病毒引起。1987年春季,检测到肠道病毒性脑膜炎的一次流行爆发,尤其是在婴儿中。这次爆发与我国不同地理区域报告的其他疫情同时发生。

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