Edmunds L H, Herrmann H C, DiSesa V J, Ratcliffe M B, Bavaria J E, McCarthy D M
Department of Surgery, School of Medicine, University of Pennsylvania, Philadelphia.
Ann Thorac Surg. 1994 Apr;57(4):880-5. doi: 10.1016/0003-4975(94)90194-5.
A method to provide left ventricular circulatory assistance without thoracotomy was developed and implemented in 2 patients. The left atrium is cannulated from the neck by passing a catheter across the interatrial septum (Dennis technique) using fluoroscopic and echocardiographic imaging. To facilitate ambulation, the arterial catheter is connected to the right axillary artery. Left atrial to axillary arterial flow is produced by a centrifugal pump. Two patients were perfused at 2.7 to 3.5 L/min for 5 and 6.5 days. One patient had successful coronary angioplasty during perfusion and remains alive 1 year later. The other patient died of sepsis and anuria that preceded implementation of circulatory assistance. The Dennis method of continuous left ventricular circulatory assistance avoids thoracotomy, requires a minimal operation, is portable and inexpensive, uses widely available equipment, and is particularly suitable for patients in cardiogenic shock after acute myocardial infarction. The method is safe and cost-effective, and merits wider application in selected patients.
一种无需开胸即可提供左心室循环辅助的方法被研发出来，并应用于2例患者。通过使用荧光透视和超声心动图成像技术，经颈将一根导管穿过房间隔（丹尼斯技术），对左心房进行插管。为便于患者行走，将动脉导管连接至右腋动脉。通过离心泵实现左心房到腋动脉的血流。2例患者以2.7至3.5升/分钟的流量灌注了5天和6.5天。其中1例患者在灌注期间成功进行了冠状动脉血管成形术，1年后仍然存活。另1例患者在循环辅助实施前死于败血症和无尿症。丹尼斯连续左心室循环辅助方法避免了开胸手术，所需手术操作 minimal，便于携带且成本低廉，使用广泛可得的设备，尤其适用于急性心肌梗死后心源性休克的患者。该方法安全且具有成本效益，值得在选定患者中更广泛地应用。 （注：原文中“minimal operation”这里的“minimal”翻译为“最小的”感觉不太准确，可能结合语境调整为更合适表述，但按要求未添加解释，所以保留原文表述）
