Said A, El-Hawary M F, Sakr R, Khalek M K, El-Shobaki F A, Noseir M B
Gaz Egypt Paediatr Assoc. 1975 Apr;23(2):139-44.
Haematological as well as biochemical parameters assessing anaemia associating protein energy malnutrition PEM were estimated. Data revealed that controls studied have a relatively lower Hb, Ht, and R.B.C.S. count than European standards. Hypochromic anaemia was predominant in 83.3% of moderate Kwashiorkor being normocytic in 50% and microcytic in 33.3%. In severe KWO anaemia was normocytic in 42% and microcytic in 19.2%. Normochromia was found in 9.7% and hypochromia in 29%. Macrocytosis was found in 38.8% in severe KWO. In marasmus, normocytic anaemia was revealed in 74% of the 2nd. grade being normochromic in 82% and hypochromic in 40%. Macrocytic anaemia was detected in 26%. In 3rd. grade subjects normocytic normochromic anaemia occurred in 70% of the cases. Macrocytosis was encountered among 30% of the cases. Serum iron and transferrin level dropped in both KWO and marasmus, the extent of decrease was greater in the former. The percent transferrin saturation was elevated in severe cases. Particularly severe KWO and marasmic KWO.
评估与蛋白质能量营养不良（PEM）相关贫血的血液学和生化参数均进行了测定。数据显示，所研究的对照组的血红蛋白（Hb）、血细胞比容（Ht）和红细胞计数（R.B.C.S.）低于欧洲标准。在中度夸希奥科病中，低色素性贫血占主导，83.3%为正细胞性贫血，50%为正细胞性贫血，33.3%为小细胞性贫血。在重度夸希奥科病中，42%为正细胞性贫血，19.2%为小细胞性贫血。9.7%为正常色素性贫血，29%为低色素性贫血。在重度夸希奥科病中，38.8%出现大细胞性贫血。在消瘦症中，74%的二级患者出现正细胞性贫血，82%为正常色素性贫血，40%为低色素性贫血。26%检测到巨细胞性贫血。在三级患者中，70%的病例出现正细胞正常色素性贫血。30%的病例出现大细胞性贫血。夸希奥科病和消瘦症患者的血清铁和转铁蛋白水平均下降，前者下降幅度更大。在严重病例中，尤其是重度夸希奥科病和消瘦型夸希奥科病患者，转铁蛋白饱和度百分比升高。
