Geddes J, Newton R, Young G, Bailey S, Freeman C, Priest R
Department of Psychiatry, Royal Edinburgh Hospital, Morningside Park.
BMJ. 1994 Mar 26;308(6932):816-9. doi: 10.1136/bmj.308.6932.816.
To determine whether the prevalence of schizophrenia among the homeless population of Edinburgh resident in hostels has changed between 1966 and 1992.
Comparison of two cross sectional surveys.
Hostels for homeless people in Edinburgh.
In 1966 a random sample of 98 residents of three common lodging houses. In 1992 a random sample of 198 residents of nine hostels.
Prevalence of schizophrenia.
The prevalence of schizophrenia in 1992 was 12/136 (9%) compared with 20/79 (25%) in 1966 (odds ratio 0.29; 95% confidence interval 0.13 to 0.62; P = 0.001). Adjustment for confounding by age, current hostel, and duration of unemployment by means of logistic regression produced an adjusted odds ratio of 0.22 (0.08 to 0.58).
The prevalence of schizophrenia was lower in 1992 even after other changes in the population resident in hostels occurring between 1966 and 1992 were taken into account. The findings are not consistent with an increase in the prevalence of schizophrenia among homeless people despite a 66% reduction in adult psychiatric beds in the region during 1966-92.
确定1966年至1992年间爱丁堡收容所中无家可归者精神分裂症的患病率是否发生了变化。
两项横断面调查的比较。
爱丁堡的无家可归者收容所。
1966年,从三间普通宿舍中随机抽取98名居民作为样本。1992年,从九间收容所中随机抽取198名居民作为样本。
精神分裂症的患病率。
1992年精神分裂症的患病率为12/136(9%),而1966年为20/79(25%)(比值比0.29;95%置信区间0.13至0.62;P = 0.001)。通过逻辑回归对年龄、当前收容所和失业持续时间的混杂因素进行调整后,调整后的比值比为0.22(0.08至0.58)。
即使考虑到1966年至1992年间收容所中其他人口变化因素,1992年精神分裂症的患病率仍较低。尽管1966 - 1992年间该地区成人精神病床位减少了66%,但这些研究结果并不支持无家可归者中精神分裂症患病率上升的观点。